1 · Identity & label claims
- Identity testing on every active ingredient — the assay that proves the bottle contains what the label names.
- Potency results for each labeled active, measured against the label claim with the method stated.
- Label-claim reconciliation: every quantitative statement on the panel traceable to a test result on file.
2 · Contaminants
- Heavy metals panel — lead, arsenic, cadmium, mercury — with numeric results and the specification each was measured against, not just “pass”.
- Residual solvents and pesticide screening where the formulation calls for it (botanical inputs especially).
3 · Microbiology
- Total aerobic count, yeast & mold, and absence testing for specified organisms (E. coli, Salmonella, S. aureus).
- Results reported per gram with the method named — reviewers reject bare checkmarks.
4 · The Certificate of Analysis itself
- Issued by an accredited third-party laboratory — ISO/IEC 17025 is the accreditation reviewers look for.
- Lot-specific: tied to the batch you are actually shipping, not a representative lot from last year.
- Method, result, specification and pass/fail on every line, with an accountable signatory.
- Formatted for the channel — a certificate written for internal QA records is a common reason a file is sent back. What a retailer actually checks on your CoA →
5 · Stability & shelf life
- Data supporting the expiry or best-by date printed on the pack — real-time or accelerated, with the protocol stated.
- For probiotics: CFU at time of fill, and stability data if you claim a count at expiry. Why fill-count labels fail review →
6 · Channel programs
- Amazon — the dietary-supplements policy requires testing documentation from an accredited lab (Transparency enrollment strengthens the listing further). Summarized from published policy; confirm current requirements with the channel.
- Whole Foods — vendor onboarding reviews ingredient standards and documentation against their quality lists.
- iHerb and specialty marketplaces — each runs its own document review; the file set above covers what they draw from.
7 · The claims file
- Substantiation on record for every claim on the pack and listing — a compliance desk’s question is always show me.
- Consumer statistics only from studies designed to produce marketing-usable evidence. When a consumer statistic is usable →
- Structure/function claims only — nothing that states or implies treatment, cure or prevention of disease. The line, in practice →
This checklist reflects the document sets curí prepares for vendor onboarding and is written for brand and regulatory teams. Individual retailer requirements change; confirm the current list with your channel contact. It is not regulatory advice on a specific product. All programs are designed to support structure/function claims permissible under DSHEA; curí does not design studies to support disease claims.